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[...] Consistent with recent reports (13, 20, 23-25), principal component analysis (PCA) using these combined datasets confirmed that the AJ individuals cluster distinctly from Europeans, aligning closest to Southern European populations along the first principal component, suggesting a more southern origin, and aligning with Central Europeans along the second, consistent with migration to this region (Fig.
S1)." Excerpts from page 16223: "The higher diversity in the AJ population was paralleled by a lower inbreeding coefficient, F, indicating the AJ population is more outbred than Europeans, not inbred, as has long been assumed (P "Through genomic analysis, researchers at Emory University School of Medicine have shown that the Ashkenazi Jewish population is genetically more diverse than people of European descent, despite previous assumptions that Ashkenazi Jews have been an isolated population.
Previous genetic studies of blood group and serum markers suggested that Jewish groups had Middle Eastern origin with greater genetic similarity between paired Jewish populations.
However, these and successor studies of monoallelic Y chromosomal and mitochondrial genetic markers did not resolve the issues of within and between-group Jewish genetic identity.
The IBD segment sharing and the proximity of European Jews to each other and to southern European populations suggested similar origins for European Jewry and refuted large-scale genetic contributions of Central and Eastern European and Slavic populations to the formation of Ashkenazi Jewry.
Rapid decay of IBD in Ashkenazi Jewish genomes was consistent with a severe bottleneck followed by large expansion, such as occurred with the so-called demographic miracle of population expansion from 50,000 people at the beginning of the 15th century to 5,000,000 people at the beginning of the 19th century.
Bray and his colleagues did find evidence of elevated linkage disequilibrium in the Ashkenazi Jewish population, but were able to show that this matches signs of interbreeding or 'admixture' between Middle Eastern and European populations.Order a DNA kit from FTDNA's headquarters in the USA This page collects Y-DNA and mt DNA data and analysis related to traditionally Rabbinical Jewish populations of the world, including: Ashkenazim (Jews of Northern and Eastern Europe) • Sephardim (Spanish and Portuguese Jews) • Mizrakhim (Middle Eastern Jews) • Italkim (Italian Jews) • Caucasian Mountain Jews (Dagestani and Azerbaijani Jews) • Georgian Jews • Indian Jews • North African Jews • Yemenite Jews • Ethiopian Jews Steven M. However, paradoxically we also found higher genetic diversity, a sign of an older or more admixed population but not of a long-term isolate. Also used for comparison were 3 Middle Eastern populations: Palestinian Arabs, Druze, and Bedouins."Abraham's Children in the Genome Era: Major Jewish Diaspora Populations Comprise Distinct Genetic Clusters with Shared Middle Eastern Ancestry." The American Journal of Human Genetics 86:6 (June 3, 2010): pages 850-859.Abstract: "For more than a century, Jews and non-Jews alike have tried to define the relatedness of contemporary Jewish people.
The researchers were able to estimate that between 35 and 55 percent of the modern Ashkenazi genome comes from European descent.